Research

Dr. Chamchad is actively involved in clinical research aimed at making anesthesia safer for patients. In cardiothorathic anesthesia his team investigates novel methods to predict post operative risks of developing cardiac arrhythmia (abnormal heart rhythm), which is a frequent complication of the open heart surgery. In obstetrics, he is working on ways of predicting and subsequently preventing possible side effects of spinal anesthesia, such as low heart rate and low blood pressure, in women undergoing planned Cesarean section.

He hopes that if possible complications of anesthesia can be predicted prior to surgery, such as abnormal heart rhythm and low blood pressure, they can be minimized or prevented altogether.

Trials currently enrolling:

Heart Rate Variability: Predictor of Cardiac Arrhythmias after Off Pump Coronary Bypass Graft Surgery.

Effect of Glycopyrrolate on Cardiac Autonomic Regulation after Spinal Anesthesia for Cesarean Section. A Randomized Double Blind Placebo Controlled Trial.

Awards and Honors

2005, Sharpe – Strumia Reseach Foundation Grant.

2002, Obstetric Anesthesia and Perinatology Society. Finalist of 'Gertie Marx' competition

2002, Competitive Research Grant (NIH based application) MCPHU

2001, Discovery 2001, 'Honorable Mention' award

1990, Pirogov's Conference for Young Scientists. First prize award

Publications

1. Dmitri Chamchad, Jacek Karski, Tirone E. David, George Djaiani, Jagdish Butany. Chronic paravalvular abscess following aortic valve replacement. Journal of Cardiothoracic and Vascular Anesthesia. Vol.18, Issue 6, Dec 2004, Pages 820-822
   
2. Nanette M. Schwann, Jay C. Horrow MD, Michael D. Strong III, Dmitri Chamchad, Albert Guerraty, Andrew S. Wechsler MD. Does Off-pump Coronary Artery Bypass Reduce the Incidence of Clinically Evident Renal Dysfunction after Multivessel Myocardial Revascularization? Anesth Analg. 2004 Oct; 99(4):959-64
   
3. Hyun Ju Jung, Dmitri Chamchad, George Djaiani, Jo Carroll, Jacek Karski, and Valerie Arkoosh. Heart Rate Variability: Predictor Of Cardiac Morbidity After CABG Surgery. Can J Anesth 2004 51: A52
   
4. Dmitri Chamchad, Valerie Arkoosh, Jay C. Horrow, Jodie Buxbaum, Igor Izrailtyan, Lev Nakhamchik, Dirk Hoyer, J. Yasha Kresh. Using Heart Rate Variability to Stratify Risk of Obstetric Patients Undergoing Spinal Anesthesia. Anesthesia and Analg. 2004 Dec; 99(6): 1818-21.
   
5. Dmitri Chamchad, George Djaiani, Alvin Chang, Jacek Karski, and Jo Carroll. A Nation-Wide Survey Of Current Clinical Practices In Management Of Cardiopulmonary Bypass In Patients Undergoing Cardiac Surgery. Can J Anesth 2003 50: 101A
   
6. Andrew A. Klein, George Djaiani, Charles Shayan, Jo Carroll, Dmitri Chamchad, Ludwik Fedorko, Davy Cheng, Jacek Karski, and Karkouti Keyvan. Acupressure Reduces Postoperative Nausea And Vomiting In Women After Cardiac Surgery. Can J Anesth 2003 50: 96A
   
7. Annett Vegas. Cardiac Anesthesiology Fellows’ Manual. 6th Edition. Dmitri Chamchad, George Djaiani. Book Chapter: Regional Anesthesia for Cardiac Surgery. In progress
   
8. Dmitri Chamchad, M.D.; Djaiani George, M.D.; Klein Andrew, M.B.B.S., FRCA; Cheng Alvin, M.D.; Karski Jacek, M.D. A Survey of the Current Clinical Practice of the Management of Cardiopulmonary Bypass in Patients Undergoing Cardiac Surgery. Anesthesiology. ASA Meeting Abstracts Oct. 2003
   
9. VS Sukhorukov, EV Tozliyan, MV Ershova, E V Polevaya, EA Shabelnikova, EA Nikolaeva, SN Illarioshkin, AV Merkurjeva, DA Chamchad. Screening mitochondrial insufficiency test in neurological patients. 35th International Danube Symposium for Neurological Sciences & Continuing Education, Sept.11-14, 2003, Belgrade, Serbia & Montenegro; P84: 140.
   
10. EV Tozliyan, EA Nikolaeva, DA Chamchad, EA Shabelnikova, AV Merkurjeva, VS Sukhorukov. Early evaluation of mitochondrial disturbances in children with non-differentiated forms of development retardation. 35th International Danube Symposium for Neurological Sciences & Continuing Education, Sept.11-14, 2003, Belgrade, Serbia & Montenegro; P85: 141-2.
    
11. Dmitri Chamchad, M.D.; George Djaiani, M.D.; Hyun Jung, M.D.; Jacek Karski, M.D.; Valerie Arkoosh, M.D. Heart Rate Variability: A Predictor of Cardiac Morbidity after Coronary Artery Bypass Graft Surgery. Anesthesiology. ASA Meeting Abstracts Oct. 2003
    
12. Dmitri Chamchad, Valerie Arkoosh, Jay Horrow, Jodie Buxbaum, Yasha Kresh. Risk Stratification for Hypotension in Obstetric Patients Undergoing Spinal Anesthesia. Anesthesiology V96: A1061, 2002
    
13. Dmitri Chamchad, Valerie Arkoosh, Jodie Buxbaum, Jay Horrow, Lev Nakhamchik, Yasha Kresh. "Peak Point Correlation Dimension: A Novel Predictor of Adverse Hemodynamic Response to Spinal Anesthesia". Anesthesiology V96, Suppl1, Apr 2002 GM-2
    
14. Nanette M. Schwann, J C Horrow, Michael D Strong, Albert Guerraty, Dmitri Chamchad. "Renal Dysfunction in Multivessel Myocardial Revascularization: Does the Off Pump Technique (OPCAB) Confer Renal Protection?" Abstract at the 2001 Annual Meeting of the American Society of Anesthesiologists. Anesthesiology 2001; 95:A248
    
15. VS Sukhorukov, DA Shamshad "Definition of spermatogenetic layer maturity level in rats during regeneration or intact testicular development" in Archives of AHE-Society [Archives of Anatomy, Histology and Embryology], 1989, N9, p.p. 88-91
    
16. VS Sukhorukov, SB Tarabryn, DA Shamshad "Usage of Sertoli-cells-only syndrome as a model for investigation of some gonadal development regulation mechanisms "Actual Problems of Medical Embryology" Siberian Depart. Of Medical Academy, AHE-Society, Irkutsk, 1989
    
17. VS Sukhorukov, SB Tarabryn, DA Shamshad, IA Darenkov, AA Dreval, OV Volkova, AK Polonsky, "The Method of male sterility treatment" Patent request N 48248664/14, priority of May 29,1990
    
18. VS Sukhorukov, SB Tarabryn, DA Shamshad "Postnatal SCO-syndrome in rats as a model for paracrine regulation and regeneration research" 4th Int. Congr. On Vertebrates Biol. Moscow, 1992
    
19. OV Volkova, SB Tarabryn, VS Sukhorukov, DA Shamshad "Paracrine regulation of male gonads. Part I. Interactions among somatic gonadal components. Part II. About the possibility of germ cell influence on somatic micro-environment" Archives of AHE-Society, 1993

Links

www.cja-jca.org/cgi/content/full/50/suppl_1/A101

www.scahq.org

www.soap.org/media/01gertiemarx.pdf