Research Summary

Dr Ezekowitz is an internationally known cardiologist with special expertise in echocardiology, thrombosis and atrial fibrillation. He has published over 200 peer-reviewed articles and book chapters. His most recent article in the New England Journal of Medicine (2005) evaluated patients in atrial fibrillation undergoing cardioversion. Dr Ezekowitz’s basic work has been funded from the NIH and Veterans Administration and he has designed several large clinical trials. One of his most highly cited articles, published in the New England Journal of Medicine (1992), proved that the blood thinning agent Coumadin® protected patients from stroke who had atrial fibrillation. The current focus of Dr. Ezekowitz's research is an experimental anti-coagulation drug that may provide an important new option for patients that have difficulty with medical treatment with Coumadin®.

Selected Publications 

1. Singh BN, Singh SN, Reda DJ, Tang XC, Lopez B, Harris CL, Fletcher RD, Sharma, SC, Atwood JE, Jacobson AK, Lewis, Jr. HD, Raisch DW, and Ezekowitz MD for the Sotalol Amiodarone Atrial Fibrillation Efficacy Trial (SAFE-T) Investigators. (2005). Amiodarone versus Sotalol for Atrial Fibrillation. N. Engl. J. Med. 352: 1861-1872.
2. Arjomand H, Cohen M, Ezekowitz MD. (2004). Combination antithrombotic therapy with antiplatelet agents and anticoagulants for patients with atherosclerotic heart disease.
   J. Invasive Cardiol.16:271-278.
3. Fiore LD, Ezekowitz MD, Brophy MT, Lu D, Sacco J, Peduzzi P; Combination Hemotherapy and Mortality Prevention (CHAMP) Study Group (2002). Department of Veterans Affairs Cooperative Studies Program Clinical Trial comparing combined warfarin and aspirin with aspirin alone in survivors of acute myocardial infarction: primary results of the CHAMP study. Circulation 105: 557-563.
4. Jagasia DH, Williams B, Ezekowitz MD. (2000). Clinical implication of antiembolic trials in atrial fibrillation and role of transesophageal echocardiography in atrial fibrillation.
   Curr. Opin. Cardiol. 15: 58-63.
5. Ezekowitz MD, Bridgers SL, James KE, Carliner NH, Colling CL, Gornick CC, Krause-Steinrauf H, Kurtzke JF, Nazarian SM, Radford MJ, et al. (1992). Warfarin in the prevention of stroke associated with nonrheumatic atrial fibrillation. Veterans Affairs Stroke Prevention in Nonrheumatic Atrial Fibrillation Investigators.
   N. Engl. J. Med. 327: 1406-1412.

Education

• M.D., University of Cape Town, Cape Town,
  South Africa
• D. Phil., Imperial College London University
• Fellow, Cardiology, Johns Hopkins Hospital

Previous Appointments

• 1978-1982 Assistant Professor
  Section of Cardiology
  Oklahoma Health Science Center
  
• 1982-1990 Associate Professor
  Department of Medicine
  Yale University School of Medicine
  
• 1990-2000 Professor with University Tenure
  Department of Medicine
  Yale University School of Medicine
• 2000-2005  Chairman and June F. Klinghoffer Professor (Cardiovascular)
  Department of Medicine
  Drexel University School of Medicine